Scopus Index Publications

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Has files: YesSubject: search.filters.subject.Optical coherence tomography

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    High-resolution optical imaging for sustainable fish freshness and safety assessment
    (Elsevier GmbH, 2026-04) Madhubhashini, M. N; Kahandawala, B.S; Sandaruwan, H.H.P. B; Silva, B.N; Wijenayake, U; Wijesinghe, R.E
    Fish freshness evaluation is crucial to ensure consumer safety, and rapid assessment is essential for effective and accurate quality control. To overcome the limitations of the gold standards, such as lack of structural depth information, high-time consumption, and labor-intensiveness, high-resolution Optical Coherence Tomography (OCT) was employed for real-time monitoring of fish freshness non-invasively. Microstructural changes of eye and skin of Indian Anchovies ( Stolephorus indicus ) specimens were considered as the main freshness parameters during refrigeration storage. Both eye and skin tissues exhibited decreased internal scattering, loss of clarity, boundary weakening, and gradual structural degradations through the OCT observations. The quantitatively assessed variance intensity, entropy, energy, and edge density clearly revealed the internal tissue disruption over storage time due to protein denaturation, oxidative damage, and fluid imbalance. The findings of this study indicate that OCT shows an insightful correlation with microbiological and biochemical spoilage processes, enabling the advanced identification of subtle microstructural changes in fish skin and eye, even at a prior stage of deterioration. Such capability offers an objective and rapid freshness evaluation approach that could greatly benefit supply chain management and post-harvest seafood quality monitoring.
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    Comparative quantifications and morphological monitoring of the topical treatment approach for onychomycosis-affected in vivo toenail using optical coherence tomography: A case study
    (Elsevier Ltd, 2024-02) Saleah, S.S; Gu, Y; Wijesinghe, R.E; Seong, D; Cho, H; Jeon, M; Kim, J
    Onychomycosis is one of the most common toenail fungal infections that affect the quality of life of many patients. Long-term and noninvasive monitoring of morphological changes of onychomycosis-affected nail plate aids the medication process and provides comfort for patients. However, existing medical and dermatological imaging methods have various types of limitations in nail investigation due to low resolution, lack of volumetric data, the necessity of highly trained personnel for image analysis, and the variety of protocols. In this study, qualitative monitoring-based quantitative assessments were performed to assess the morphological changes of onychomycosis-affected toenail for 15 consecutive weeks using high-resolution optical coherence tomography (OCT). Layer intensity and surface roughness measuring algorithms were applied to two-dimensional OCT cross-sectional images to detect gradual changes in the morphological structure of the diseased toenail. A depth intensity profile and the angle formed between the nail plate and nail fold were also used to analyze the thickness and shape of the toenail plates, respectively. The quantitative and morphological monitoring results revealed significant changes in the toenail structure before and during the treatment process, confirming the healing of the diseased toenail. Therefore, the proposed noninvasive optical analysis approach can be applied to monitor nail abnormalities and evaluate the process of diseased toenail medication
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    Non-destructive morphological screening for the assessment of postharvest storage effect on pears stored with apples using optical coherence tomography
    (Elsevier GmbH, 2024-04) Luna, J.A; Wijesinghe, R.E; Lee, S.Y; Ravichandran, N.K; Saleah, S.A; Seong, D; Jung, H.Y; Jeon, M; Kim, J
    The use of a limited and inadequate storage facility for the storage of multiple food items for an extended period of time results in the loss of structural integrity and freshness while storing fruit in confined single storage without adequate individual packaging methods can result in morphological changes and the degradation of the quality of the fruit. In this study, the effects of postharvest storage on pears co-stored with apples were investigated via non-invasive screening of the structural deformation of pears and the respective anatomical changes of the sub-surface. The anatomical changes were monitored for a prolonged time (12 d) under inadequate and confined storage conditions using swept-source optical coherence tomography (SS-OCT) and the results were comparatively analyzed using appropriately stored specimens. In addition, the OCT cross-sectional images were analyzed for the assessment of the dispersed intensity profile using a customized intensity-based image-processing algorithm. The results revealed the internal morphological variations and corresponding intensity fluctuations, thickness variations, and internal gap formations. This confirmed the potential applicability of OCT as a real-time, non-invasive high-resolution assessment technique for determining fruit quality in diverse environments, such as post-harvest storage and transportation systems.
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    Comparative quantifications and morphological monitoring of the topical treatment approach for onychomycosis-affected in vivo toenail using optical coherence tomography: A case study
    (Elsevier, 2023-10-19) Saleah, S. A; Gu, Y; Wijesinghe, R.E; Seong, D; Cho, H; Jeon, M; Kim, J
    Onychomycosis is one of the most common toenail fungal infections that affect the quality of life of many patients. Long-term and noninvasive monitoring of morphological changes of onychomycosis-affected nail plate aids the medication process and provides comfort for patients. However, existing medical and dermatological imaging methods have various types of limitations in nail investigation due to low resolution, lack of volumetric data, the necessity of highly trained personnel for image analysis, and the variety of protocols. In this study, qualitative monitoring-based quantitative assessments were performed to assess the morphological changes of onychomycosis-affected toenail for 15 consecutive weeks using high-resolution optical coherence tomography (OCT). Layer intensity and surface roughness measuring algorithms were applied to two-dimensional OCT cross-sectional images to detect gradual changes in the morphological structure of the diseased toenail. A depth intensity profile and the angle formed between the nail plate and nail fold were also used to analyze the thickness and shape of the toenail plates, respectively. The quantitative and morphological monitoring results revealed significant changes in the toenail structure before and during the treatment process, confirming the healing of the diseased toenail. Therefore, the proposed noninvasive optical analysis approach can be applied to monitor nail abnormalities and evaluate the process of diseased toenail medication.