Ai-Based Urine Microscopy Image Analysis for Predicting Urinary Tract and Renal Diseases

Abstract

The manual microscopic examination of urine is a crucial step in diagnosis of urinary tract and renal diseases. However, the process is time-consuming and operator dependent. Most of the existing automated urinalysis techniques only consider the microscopic examination of individual components or the black-box-based prediction models. There is a lack of a comprehensive framework that incorporates the microscopic examination of the microscopic components with the clinical diagnostic logic. In this regard, the present work proposes an artificial intelligence-based urinalysis system for the microscopic examination of the components in the urine sample to generate diagnostic outcomes. In the proposed system, the microscopic components like white blood cells, red blood cells, bacteria, yeast, crystals, and casts are detected and analyzed to generate the diagnostic outcomes for the diagnosis of urinary tract infection, kidney stone risk, hematuria causes, and casts-related renal diseases. In the proposed system, efficient lightweight models ensure precision and effectiveness in identifying various biological entities. White blood cells are detected with a mAP@0.5 score of 0.96, yeast with over 0.94, and crystals with more than 0.91, yielding a classification accuracy of 99.41% for crystals. The system detects microscopic elements like casts with a mAP@0.5 score of 0.80. The system also incorporates auxiliary clinical data to enhance diagnostic results for various diseases.